Reaction Details
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Report a problem with these dataTarget
Norepinephrine transporter
Ligand
BDBM50136674
Substrate
n/a
Ki
15.9±n/a nM
Comments
PDSP_2398
Citation
Wong, DT; Bymaster, FP; Mayle, DA; Reid, LR; Krushinski, JH; Robertson, DW LY248686, a new inhibitor of serotonin and norepinephrine uptake. Neuropsychopharmacology 8:23-33 (1993) [PubMed] Article More Info.:
Target
Name:
Norepinephrine transporter
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
2082.45
Organism:
RAT
Description:
Norepinephrine transporter 0 RAT::Q9JIA2
Residue:
19
Sequence:
MLLARMKPQVQPELGGADQ
Inhibitor
Name:
BDBM50136674
Synonyms:
(3R)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propan-1-amine | (3R)-N-methyl-3-(naphthalen-1-yloxy)-3-(2-thienyl)propan-1-amine | (R)-duloxetine | CHEMBL336920 | LY248685
Type:
Small organic molecule
Emp. Form.:
C18H19NOS
Mol. Mass.:
297.415
SMILES:
CNCC[C@@H](Oc1cccc2ccccc12)c1cccs1 |r|
Structure:
