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Target
Glucose-dependent insulinotropic receptor
Ligand
BDBM50387891
Substrate
n/a
Meas. Tech.
ChEMBL_830702 (CHEMBL2061689)
EC50
210±n/a nM
Citation
 Sakairi, M; Kogami, M; Torii, M; Kataoka, H; Fujieda, H; Makino, M; Kataoka, D; Okamoto, R; Miyazawa, T; Okabe, M; Inoue, M; Takahashi, N; Harada, S; Watanabe, N Synthesis and SAR studies of bicyclic amine series GPR119 agonists. Bioorg Med Chem Lett 22:5123-8 (2012) [PubMed]  Article 
Target
Name:
Glucose-dependent insulinotropic receptor
Synonyms:
G-protein coupled receptor 119 (GPR119) | GP119_HUMAN | GPR119 | Glucose-dependent insulinotropic receptor
Type:
Protein
Mol. Mass.:
36901.49
Organism:
Homo sapiens (Human)
Description:
Q8TDV5
Residue:
335
Sequence:
MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISGLLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLKIMSGFVAGACIAGLWLVSYLIGFLPLGIPMFQQTAYKGQCSFFAVFHPHFVLTLSCVGFFPAMLLFVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFKALRTVSVLIGSFALSWTPFLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKVLTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
  
Inhibitor
Name:
BDBM50387891
Synonyms:
CHEMBL2058389
Type:
Small organic molecule
Emp. Form.:
C22H34N2O4S
Mol. Mass.:
422.581
SMILES:
CC(C)(C)OC(=O)N1CCC(CCCCNc2ccc3c(CCS3(=O)=O)c2)CC1
Structure:
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