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Target
D(3) dopamine receptor
Ligand
BDBM50394930
Substrate
n/a
Meas. Tech.
ChEMBL_860682 (CHEMBL2167999)
Ki
197.4±n/a nM
Citation
 Newman, AH; Beuming, T; Banala, AK; Donthamsetti, P; Pongetti, K; LaBounty, A; Levy, B; Cao, J; Michino, M; Luedtke, RR; Javitch, JA; Shi, L Molecular determinants of selectivity and efficacy at the dopamine D3 receptor. J Med Chem 55:6689-99 (2012) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50394930
Synonyms:
CHEMBL1424807
Type:
Small organic molecule
Emp. Form.:
C10H12Cl2N2
Mol. Mass.:
231.122
SMILES:
Clc1cccc(N2CCNCC2)c1Cl
Structure:
Search PDB for entries with ligand similarity: