Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50396933
Substrate
n/a
Meas. Tech.
ChEMBL_862921 (CHEMBL2174885)
Ki
2200±n/a nM
Citation
 Tosh, DK; Paoletta, S; Deflorian, F; Phan, K; Moss, SM; Gao, ZG; Jiang, X; Jacobson, KA Structural sweet spot for A1 adenosine receptor activation by truncated (N)-methanocarba nucleosides: receptor docking and potent anticonvulsant activity. J Med Chem 55:8075-90 (2012) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50396933
Synonyms:
CHEMBL2170794
Type:
Small organic molecule
Emp. Form.:
C21H22ClN5O2
Mol. Mass.:
411.885
SMILES:
O[C@@H]1[C@@H]2C[C@@H]2[C@H]([C@@H]1O)n1cnc2c(N[C@@H](C3CC3)c3ccccc3)nc(Cl)nc12 |r|
Structure:
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