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Target
5-hydroxytryptamine receptor 1A
Ligand
BDBM50403508
Substrate
n/a
Meas. Tech.
ChEBML_1011
IC50
1.3±n/a nM
Citation
 Lommen, GV; De Bruyn, M; Schroven, M; Verschueren, W; Janssens, W; Verrelst, J; Leysen, J The discovery of a series of new non-indole 5HT1D agonists Bioorg Med Chem Lett 5:2649-2654 (1995)    Article 
Target
Name:
5-hydroxytryptamine receptor 1A
Synonyms:
5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A
Type:
n/a
Mol. Mass.:
46122.49
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
422
Sequence:
MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ
  
Inhibitor
Name:
BDBM50403508
Synonyms:
CHEMBL88207
Type:
Small organic molecule
Emp. Form.:
C18H23N3O
Mol. Mass.:
297.3947
SMILES:
C(CNCC1CCc2ccccc2O1)CNc1ccccn1
Structure:
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