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TargetAdenosine kinase
LigandBDBM50090865
Substrate/Competitorn/a
Meas. Tech.ChEBML_31135
IC50 831763771±n/a nM
Citation González, MPMoldes del Carmen Terán, M A TOPS-MODE approach to predict adenosine kinase inhibition. Bioorg Med Chem Lett14:3077-9 (2004) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Adenosine kinase
Name:Adenosine kinase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:40545.97
Organism:Homo sapiens (Human)
Description:ChEMBL_1467841
Residue:362
Sequence:
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAED
KHKELFDELVKKFKVEYHAGGSTQNSIKVAQWMIQQPHKAATFFGCIGIDKFGEILKRKA
AEAHVDAHYYEQNEQPTGTCAACITGDNRSLIANLAAANCYKKEKHLDLEKNWMLVEKAR
VCYIAGFFLTVSPESVLKVAHHASENNRIFTLNLSAPFISQFYKESLMKVMPYVDILFGN
ETEAATFAREQGFETKDIKEIAKKTQALPKMNSKRQRIVIFTQGRDDTIMATESEVTAFA
VLDQDQKEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASIIIRRTGCTFPEKPD
FH
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  Blast E-value cutoff:
BDBM50090865
NameBDBM50090865
Synonyms:(2R,3R,4S,5R)-2-(4-Amino-5-iodo-pyrrolo[2,3-d]pyrimidin-7-yl)-5-methoxymethyl-tetrahydro-furan-3,4-diol | (2R,3R,4S,5R)-2-(4-amino-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(methoxymethyl)-tetrahydrofuran-3,4-diol | 2-(4-Amino-5-iodo-pyrrolo[2,3-d]pyrimidin-7-yl)-5-methoxymethyl-tetrahydro-furan-3,4-diol | CHEMBL322217
TypeSmall organic molecule
Emp. Form.C12H15IN4O4
Mol. Mass.406.1764
SMILESCOC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc(I)c2c(N)ncnc12 |r|
Structure
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n/a