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Target
5-hydroxytryptamine receptor 2B
Ligand
BDBM50404641
Substrate
n/a
Meas. Tech.
ChEMBL_2901 (CHEMBL875914)
Kd
302±n/a nM
Citation
 Glennon, RA; Liebowitz, SM; Leming-Doot, D; Rosecrans, JA Demethyl analogues of psychoactive methoxyphenalkylamines: synthesis and serotonin receptor affinities. J Med Chem 23:990-4 (1980) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 2B
Synonyms:
5-HT2B | 5-hydroxytryptamine receptor 2B | 5HT2B_RAT | Htr2b | Serotonin 2b (5-HT2b) receptor | Serotonin receptor 2a and 2b (5HT2A and 5HT2B) | Srl
Type:
Enzyme Catalytic Domain
Mol. Mass.:
53668.47
Organism:
RAT
Description:
5-HT2B HTR2B RAT::P30994
Residue:
479
Sequence:
MASSYKMSEQSTISEHILQKTCDHLILTDRSGLKAESAAEEMKQTAENQGNTVHWAALLIFAVIIPTIGGNILVILAVSLEKRLQYATNYFLMSLAVADLLVGLFVMPIALLTIMFEATWPLPLALCPAWLFLDVLFSTASIMHLCAISLDRYIAIKKPIQANQCNSRTTAFVKITVVWLISIGIAIPVPIKGIEADVVNAHNITCELTKDRFGSFMLFGSLAAFFAPLTIMIVTYFLTIHALRKKAYLVRNRPPQRLTRWTVSTVLQREDSSFSSPEKMVMLDGSHKDKILPNSTDETLMRRMSSAGKKPAQTISNEQRASKVLGIVFLFFLLMWCPFFITNVTLALCDSCNQTTLKTLLQIFVWVGYVSSGVNPLIYTLFNKTFREAFGRYITCNYQATKSVKVLRKCSSTLYFGNSMVENSKFFTKHGIRNGINPAMYQSPVRLRSSTIQSSSIILLNTFLTENDGDKVEDQVSYI
  
Inhibitor
Name:
BDBM50404641
Synonyms:
CHEMBL174563
Type:
Small organic molecule
Emp. Form.:
C11H17NO2
Mol. Mass.:
195.2582
SMILES:
COc1ccc(O)c(CCN(C)C)c1
Structure:
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