Reaction Details Report a problem with these data
Target
Beta-1 adrenergic receptor
Ligand
BDBM50404761
Substrate
n/a
Meas. Tech.
ChEMBL_37085 (CHEMBL650926)
Kd
398±n/a nM
Citation
 Erhardt, PW; Woo, CM; Gorczynski, RJ; Anderson, WG Ultra-short-acting beta-adrenergic receptor blocking agents. 1. (Aryloxy)propanolamines containing esters in the nitrogen substituent. J Med Chem 25:1402-7 (1983) [PubMed]  Article 
Target
Name:
Beta-1 adrenergic receptor
Synonyms:
ADRB1 | Adrenergic receptor | adrenergic Beta1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50540.48
Organism:
GUINEA PIG
Description:
adrenergic Beta1 ADRB1 GUINEA PIG::B0FL73
Residue:
467
Sequence:
MGAGVLALGASEPCNLSSTAPLPDGAATAARLLVPASPPASLLPPTSEGSEPLSPQWTAGMGLLMVLIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARVLVCTVWAISALVSFLPILMHWWRAEGDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIMAFVYLRVFREAQKQVKKIDSCERRFLGGPGRPPSPVPSPTPGSPRAATDPLANGRTSKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANSAFNPIIYCRSPDFRKAFQRLLCCARRAARRRHTAHGGRPRASGCLARSGPPPSPGAASDEDEDAVGAAPPARLLEPWAGCNGGAATADSDWSLDEPGRAGFASESKV
  
Inhibitor
Name:
BDBM50404761
Synonyms:
CHEMBL30558
Type:
Small organic molecule
Emp. Form.:
C18H21NO4
Mol. Mass.:
315.3636
SMILES:
OC(CNCCC(=O)Oc1ccccc1)COc1ccccc1
Structure:
Search PDB for entries with ligand similarity: