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Target
Beta-1 adrenergic receptor
Ligand
BDBM25753
Substrate
n/a
Meas. Tech.
ChEMBL_39350 (CHEMBL654957)
Kd
24±n/a nM
Citation
 Baldwin, JJ; Denny, GH; Hirschmann, R; Freedman, MB; Ponticello, GS; Gross, DM; Sweet, CS Beta 1-selective adrenoceptor antagonists: examples of the 2-[4-[3-(substituted-amino)-2-hydroxypropoxy]phenyl]imidazole class. J Med Chem 26:950-7 (1983) [PubMed]  Article 
Target
Name:
Beta-1 adrenergic receptor
Synonyms:
ADRB1 | Adrenergic receptor | adrenergic Beta1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50540.48
Organism:
GUINEA PIG
Description:
adrenergic Beta1 ADRB1 GUINEA PIG::B0FL73
Residue:
467
Sequence:
MGAGVLALGASEPCNLSSTAPLPDGAATAARLLVPASPPASLLPPTSEGSEPLSPQWTAGMGLLMVLIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARVLVCTVWAISALVSFLPILMHWWRAEGDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIMAFVYLRVFREAQKQVKKIDSCERRFLGGPGRPPSPVPSPTPGSPRAATDPLANGRTSKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANSAFNPIIYCRSPDFRKAFQRLLCCARRAARRRHTAHGGRPRASGCLARSGPPPSPGAASDEDEDAVGAAPPARLLEPWAGCNGGAATADSDWSLDEPGRAGFASESKV
  
Inhibitor
Name:
BDBM25753
Synonyms:
2-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl}acetamide | Artrenolol | Atenolol | CHEMBL24 | Tenormin | Tenormine
Type:
Small organic molecule
Emp. Form.:
C14H22N2O3
Mol. Mass.:
266.3361
SMILES:
CC(C)NCC(O)COc1ccc(CC(N)=O)cc1
Structure:
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