Reaction Details Report a problem with these data
Target
Adenosylhomocysteinase
Ligand
BDBM50405655
Substrate
n/a
Meas. Tech.
ChEBML_197202
Ki
35±n/a nM
Citation
 Narayanan, SR; Keller, BT; Borcherding, DR; Scholtz, SA; Borchardt, RT 9-(trans-2',trans-3'-dihydroxycyclopent-4'-enyl) derivatives of adenine and 3-deazaadenine: potent inhibitors of bovine liver S-adenosylhomocysteine hydrolase. J Med Chem 31:500-3 (1988) [PubMed]  Article 
Target
Name:
Adenosylhomocysteinase
Synonyms:
AHCY | Adenosylhomocysteinase | SAHH | SAHH_HUMAN
Type:
PROTEIN
Mol. Mass.:
47714.06
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1507791
Residue:
432
Sequence:
MSDKLPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY
  
Inhibitor
Name:
BDBM50405655
Synonyms:
CHEMBL147260
Type:
Small organic molecule
Emp. Form.:
C11H12N4O2
Mol. Mass.:
232.2386
SMILES:
Nc1nccc2n(cnc12)C1C=C[C@@H](O)[C@H]1O |c:13|
Structure:
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