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Target
7-dehydrocholesterol reductase
Ligand
BDBM50406621
Substrate
n/a
Meas. Tech.
ChEBML_53601
Ki
4±n/a nM
Citation
 Ator, MA; Schmidt, SJ; Adams, JL; Dolle, RE; Kruse, LI; Frey, CL; Barone, JM Synthesis, specificity, and antifungal activity of inhibitors of the Candida albicans delta 24-sterol methyltransferase. J Med Chem 35:100-6 (1992) [PubMed]  Article 
Target
Name:
7-dehydrocholesterol reductase
Synonyms:
DHCR7_RAT | Dhcr7
Type:
PROTEIN
Mol. Mass.:
54168.97
Organism:
Rattus norvegicus
Description:
ChEMBL_53595
Residue:
471
Sequence:
MASKSQHNASKAKNHNVKAESQGQWGRAWEVDWFSLVSVIFLLLFAPFIVYYFIMACDQYSCSLTAPILDVATGRASLADIWAKTPPVTAKAAQLYALWVSFQVLLYSWLPDFCHRFLPGYVGGVQEGAITPAGIVNKYEVNGLQAWLITHFLWFVNAYLLSWFSPTIIFDNWIPLLWCANILGYAVSTFAMIKGYLFPTSAEDCKFTGNFFYNYMMGIEFNPRIGKWFDFKLFFNGRPGIVAWTLINLSFAAKQQELYGHVTNSMILVNVLQAIYVLDFFWNETWYLKTIDICHDHFGWYLGWGDCVWLPYLYTLQGLYLVYHPVQLSTPNALGVLLLGLVGYYIFRMTNHQKDLFRRTDGHCLIWGKKPKAIECSYTSADGLKHRSKLLVSGFWGVARHFNYTGDLMGSLAYCLACGGGHLLPYFYIIYMTILLTHRCLRDEHRCANKYGRDWERYVAAVPYRLLPGIF
  
Inhibitor
Name:
BDBM50406621
Synonyms:
CHEMBL9820
Type:
Small organic molecule
Emp. Form.:
C27H47OS
Mol. Mass.:
419.726
SMILES:
C[C@H](CC[S+](C)C(C)C)C1CCC2C3CC=C4C[C@@H](O)CC[C@]4(C)C3CC[C@]12C |t:15|
Structure:
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