Reaction Details Report a problem with these data
Target
Acyl carrier protein, mitochondrial
Ligand
BDBM50411083
Substrate
n/a
Meas. Tech.
ChEMBL_373476 (CHEMBL853536)
IC50
45±n/a nM
Citation
 Ichimaru, N; Abe, M; Murai, M; Senoh, M; Nishioka, T; Miyoshi, H Function of the alkyl side chains of Deltalac-acetogenins in the inhibitory effect on mitochondrial complex I (NADH-ubiquinone oxidoreductase). Bioorg Med Chem Lett 16:3555-8 (2006) [PubMed]  Article 
Target
Name:
Acyl carrier protein, mitochondrial
Synonyms:
ACP | ACPM_BOVIN | CI-SDAP | NADH-ubiquinone oxidoreductase 9.6 kDa subunit | NDUFAB1
Type:
PROTEIN
Mol. Mass.:
17397.64
Organism:
Bos taurus
Description:
ChEMBL_469770
Residue:
156
Sequence:
MAVRVLCACVRRLPTAFAPLPRLPTLAAARPLSTTLFAAETRTRPGAPLPALVLAQVPGRVTQLCRQYSDAPPLTLEGIKDRVLYVLKLYDKIDPEKLSVNSHFMKDLGLDSLDQVEIIMAMEDEFGFEIPDIDAEKLMCPQEIVDYIADKKDVYE
  
Inhibitor
Name:
BDBM50411083
Synonyms:
CHEMBL379529
Type:
Small organic molecule
Emp. Form.:
C22H42O4
Mol. Mass.:
370.5665
SMILES:
CCCCCCCCCC[C@@H](O)[C@H]1CC[C@@H](O1)[C@H]1CC[C@@H](O1)[C@H](O)CC
Structure:
Search PDB for entries with ligand similarity: