Reaction Details Report a problem with these data
Target
Acyl carrier protein, mitochondrial
Ligand
BDBM50130143
Substrate
n/a
Meas. Tech.
ChEMBL_373476 (CHEMBL853536)
IC50
4500±n/a nM
Citation
 Ichimaru, N; Abe, M; Murai, M; Senoh, M; Nishioka, T; Miyoshi, H Function of the alkyl side chains of Deltalac-acetogenins in the inhibitory effect on mitochondrial complex I (NADH-ubiquinone oxidoreductase). Bioorg Med Chem Lett 16:3555-8 (2006) [PubMed]  Article 
Target
Name:
Acyl carrier protein, mitochondrial
Synonyms:
ACP | ACPM_BOVIN | CI-SDAP | NADH-ubiquinone oxidoreductase 9.6 kDa subunit | NDUFAB1
Type:
PROTEIN
Mol. Mass.:
17397.64
Organism:
Bos taurus
Description:
ChEMBL_469770
Residue:
156
Sequence:
MAVRVLCACVRRLPTAFAPLPRLPTLAAARPLSTTLFAAETRTRPGAPLPALVLAQVPGRVTQLCRQYSDAPPLTLEGIKDRVLYVLKLYDKIDPEKLSVNSHFMKDLGLDSLDQVEIIMAMEDEFGFEIPDIDAEKLMCPQEIVDYIADKKDVYE
  
Inhibitor
Name:
BDBM50130143
Synonyms:
(R)-1-[(2R,5R,2'R,5'R)-5'-((R)-1-hydroxy-hexyl)-octahydro-[2,2']bifuranyl-5-yl]-hexan-1-ol | (R)-1-[(2R,5R,4'R)-5'-((1R,2R)-1-Hydroxy-hexyl)-octahydro-[2,2']bifuranyl-5-yl]-hexan-1-ol | CHEMBL80354
Type:
Small organic molecule
Emp. Form.:
C20H38O4
Mol. Mass.:
342.5133
SMILES:
CCCCC[C@@H](O)[C@H]1CC[C@@H](O1)[C@H]1CC[C@@H](O1)[C@H](O)CCCCC
Structure:
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