Reaction Details Report a problem with these data
Target
Acyl carrier protein, mitochondrial
Ligand
BDBM50411912
Substrate
n/a
Meas. Tech.
ChEMBL_469770 (CHEMBL948046)
IC50
>26500±n/a nM
Citation
 Surup, F; Shojaei, H; von Zezschwitz, P; Kunze, B; Grond, S Iromycins from Streptomyces sp. and from synthesis: new inhibitors of the mitochondrial electron transport chain. Bioorg Med Chem 16:1738-46 (2008) [PubMed]  Article 
Target
Name:
Acyl carrier protein, mitochondrial
Synonyms:
ACP | ACPM_BOVIN | CI-SDAP | NADH-ubiquinone oxidoreductase 9.6 kDa subunit | NDUFAB1
Type:
PROTEIN
Mol. Mass.:
17397.64
Organism:
Bos taurus
Description:
ChEMBL_469770
Residue:
156
Sequence:
MAVRVLCACVRRLPTAFAPLPRLPTLAAARPLSTTLFAAETRTRPGAPLPALVLAQVPGRVTQLCRQYSDAPPLTLEGIKDRVLYVLKLYDKIDPEKLSVNSHFMKDLGLDSLDQVEIIMAMEDEFGFEIPDIDAEKLMCPQEIVDYIADKKDVYE
  
Inhibitor
Name:
BDBM50411912
Synonyms:
IROMYCIN D
Type:
Small organic molecule
Emp. Form.:
C18H27NO3
Mol. Mass.:
305.4119
SMILES:
CCCc1c(C\C=C(/C)C\C=C\C(C)O)[nH]c(=O)c(C)c1O
Structure:
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