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TargetD(1A) dopamine receptor
LigandBDBM50201338
Substrate/Competitorn/a
Meas. Tech.ChEMBL_491079
Ki 0.562±n/a nM
Citation Enzensperger, CGörnemann, TPertz, HHLehmann, J Dopamine/serotonin receptor ligands. Part 17: a cross-target SAR approach: affinities of azecine-styled ligands for 5-HT(2A) versus D1 and D2 receptors. Bioorg Med Chem Lett18:3809-13 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
D(1A) dopamine receptor
Name:Dopamine D1 and D2 receptor
Synonyms:DA D1 receptor | DOPAMINE D1 | DRD1 | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A
Type:Enzyme
Mol. Mass.:49303.43
Organism:Homo sapiens (Human)
Description:P21728
Residue:446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTN
FFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVD
RYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLA
ETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKN
CQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGS
GETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIET
VSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPAL
SVILDYDTDVSLEKIQPITQNGQHPT
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50201338
NameBDBM50201338
Synonyms:7-methyl-6,7,8,9,14,15-hexahydro-5H-indolo[3,2-f][3]benzazecin-11-ol | CHEMBL245570
TypeSmall organic molecule
Emp. Form.C20H22N2O
Mol. Mass.306.4015
SMILESCN1CCc2c(Cc3ccccc3CC1)[nH]c1ccc(O)cc21
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a