Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50170339
Substrate
n/a
Meas. Tech.
ChEMBL_570539 (CHEMBL1026911)
Ki
146.22±n/a nM
Citation
 De Freitas, GB; da Silva, LL; Romeiro, NC; Fraga, CA Development of CoMFA and CoMSIA models of affinity and selectivity for indole ligands of cannabinoid CB1 and CB2 receptors. Eur J Med Chem 44:2482-96 (2009) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50170339
Synonyms:
1-(1-Pentyl-1H-indol-3-yl)-2-o-tolyl-ethanone | 1-(1-pentyl-1H-indol-3-yl)-2-o-tolylethanone | CHEMBL364820 | JWH-251
Type:
Small organic molecule
Emp. Form.:
C22H25NO
Mol. Mass.:
319.44
SMILES:
CCCCCn1cc(C(=O)Cc2ccccc2C)c2ccccc12
Structure:
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