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Target
Alpha-2B adrenergic receptor
Ligand
BDBM81807
Substrate
n/a
Meas. Tech.
ChEMBL_664776 (CHEMBL1259386)
Ki
2.2±n/a nM
Citation
 Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M Rigid analogues of thea2-adrenergic blocker atipamezole: small changes, big consequences. J Med Chem 53:6986-95 (2010) [PubMed]  Article 
Target
Name:
Alpha-2B adrenergic receptor
Synonyms:
ADA2B_HUMAN | ADRA2B | ADRA2L1 | ADRA2RL1 | Adrenergic alpha2B | Adrenergic receptor | Adrenergic receptor alpha | Adrenergic, alpha-2B-, receptor [Homo sapiens] | Alpha-2 adrenergic receptor subtype C2 | Alpha-2B adrenoceptor | Alpha-2B adrenoreceptor | Alpha-2BAR
Type:
Enzyme
Mol. Mass.:
49964.20
Organism:
Homo sapiens (Human)
Description:
P18089
Residue:
450
Sequence:
MDHQDPYSVQATAAIAAAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADILVATLIIPFSLANELLGYWYFRRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEYNSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQGPQPRGRPQCKLNQEAWYILASSIGSFFAPCLIMILVYLRIYLIAKRSNRRGPRAKGGPGQGESKQPRPDHGGALASAKLPALASVASAREVNGHSKSTGEKEEGETPEDTGTRALPPSWAALPNSGQGQKEGVCGASPEDEAEEEEEEEEEEEECEPQAVPVSPASACSPPLQQPQGSRVLATLRGQVLLGRGVGAIGGQWWRRRAQLTREKRFTFVLAVVIGVFVLCWFPFFFSYSLGAICPKHCKVPHGLFQFFFWIGYCNSSLNPVIYTIFNQDFRRAFRRILCRPWTQTAW
  
Inhibitor
Name:
BDBM81807
Synonyms:
ATIPAMEZOLE | CAS_104054-27-5 | NSC_71310
Type:
Small organic molecule
Emp. Form.:
C14H16N2
Mol. Mass.:
212.2902
SMILES:
CCC1(Cc2ccccc2C1)c1cnc[nH]1
Structure:
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