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Target
Alpha-2A adrenergic receptor
Ligand
BDBM50417007
Substrate
n/a
Meas. Tech.
ChEMBL_664775 (CHEMBL1259385)
Ki
7.2±n/a nM
Citation
 Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M Rigid analogues of thea2-adrenergic blocker atipamezole: small changes, big consequences. J Med Chem 53:6986-95 (2010) [PubMed]  Article 
Target
Name:
Alpha-2A adrenergic receptor
Synonyms:
ADA2A_HUMAN | ADRA2A | ADRA2R | ADRAR | Adrenergic alpha2A | Adrenergic receptor alpha | Alpha-2 adrenergic receptor subtype C10 | Alpha-2A adrenoceptor | Alpha-2A adrenoreceptor | Alpha-2AAR | alpha-2A adrenergic receptor [Homo sapiens]
Type:
Enzyme
Mol. Mass.:
48979.91
Organism:
Homo sapiens (Human)
Description:
P08913
Residue:
450
Sequence:
MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV
  
Inhibitor
Name:
BDBM50417007
Synonyms:
FIPAMEZOLE
Type:
Small organic molecule
Emp. Form.:
C14H15FN2
Mol. Mass.:
230.2807
SMILES:
CCC1(Cc2ccc(F)cc2C1)c1cnc[nH]1
Structure:
Search PDB for entries with ligand similarity: