Reaction Details Report a problem with these data
Target
Cytochrome P450 1A1
Ligand
BDBM50027785
Substrate
n/a
Meas. Tech.
ChEMBL_774160 (CHEMBL1908255)
Ki
250±n/a nM
Citation
 Fontana, E; Dansette, PM; Poli, SM Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity. Curr Drug Metab 6:413-54 (2005) [PubMed]  Article 
Target
Name:
Cytochrome P450 1A1
Synonyms:
CP1A1_RAT | Cyp1a-1 | Cyp1a1
Type:
PROTEIN
Mol. Mass.:
59401.56
Organism:
Rattus norvegicus
Description:
ChEMBL_774160
Residue:
524
Sequence:
MPSVYGFPAFTSATELLLAVTTFCLGFWVVRVTRTWVPKGLKSPPGPWGLPFIGHVLTLGKNPHLSLTKLSQQYGDVLQIRIGSTPVVVLSGLNTIKQALVKQGDDFKGRPDLYSFTLIANGQSMTFNPDSGPLWAARRRLAQNALKSFSIASDPTLASSCYLEEHVSKEAEYLISKFQKLMAEVGHFDPFKYLVVSVANVICAICFGRRYDHDDQELLSIVNLSNEFGEVTGSGYPADFIPILRYLPNSSLDAFKDLNKKFYSFMKKLIKEHYRTFEKGHIRDITDSLIEHCQDRRLDENANVQLSDDKVITIVFDLFGAGFDTITTAISWSLMYLVTNPRIQRKIQEELDTVIGRDRQPRLSDRPQLPYLEAFILETFRHSSFVPFTIPHSTIRDTSLNGFYIPKGHCVFVNQWQVNHDQELWGDPNEFRPERFLTSSGTLDKHLSEKVILFGLGKRKCIGETIGRLEVFLFLAILLQQMEFNVSPGEKVDMTPAYGLTLKHARCEHFQVQMRSSGPQHLQA
  
Inhibitor
Name:
BDBM50027785
Synonyms:
2-Ethynyl Phenanthrene | CHEMBL1908225
Type:
Small organic molecule
Emp. Form.:
C16H10
Mol. Mass.:
202.2506
SMILES:
C#Cc1ccc2c(ccc3ccccc23)c1
Structure:
Search PDB for entries with ligand similarity: