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Target
D(2) dopamine receptor
Ligand
BDBM50421924
Substrate
n/a
Meas. Tech.
ChEBML_60934
IC50
288±n/a nM
Citation
 Russell, MG; Baker, R; Billington, DC; Knight, AK; Middlemiss, DN; Noble, AJ Benz[f]isoquinoline analogues as high-affinity sigma ligands. J Med Chem 35:2025-33 (1992) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50421924
Synonyms:
CHEMBL544280
Type:
Small organic molecule
Emp. Form.:
C24H31N
Mol. Mass.:
333.5096
SMILES:
CC(C)(C)c1ccc(CN2CC[C@@H]3[C@@H](CCc4ccccc34)C2)cc1 |r|
Structure:
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