Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50423867
Substrate
n/a
Meas. Tech.
ChEMBL_817485 (CHEMBL2027708)
Kd
21±n/a nM
Citation
 Vernall, AJ; Stoddart, LA; Briddon, SJ; Hill, SJ; Kellam, B Highly potent and selective fluorescent antagonists of the human adenosine A3 receptor based on the 1,2,4-triazolo[4,3-a]quinoxalin-1-one scaffold. J Med Chem 55:1771-82 (2012) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50423867
Synonyms:
CHEMBL2023737
Type:
Small organic molecule
Emp. Form.:
C26H31N7O6
Mol. Mass.:
537.5676
SMILES:
COc1ccc(cc1)-n1nc2c(NC(=O)CCC(=O)NCCOCCOCCN)nc3ccccc3n2c1=O
Structure:
Search PDB for entries with ligand similarity: