Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetAcetolactate synthase catalytic subunit, mitochondrial
LigandBDBM50424588
Substrate/Competitorn/a
Meas. Tech.ChEMBL_934102
Ki 51±n/a nM
Citation Lee, YTCui, CJChow, EWPue, NLonhienne, TWang, JGFraser, JAGuddat, LW Sulfonylureas have antifungal activity and are potent inhibitors of Candida albicans acetohydroxyacid synthase. J Med Chem56:210-9 (2013) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Acetolactate synthase catalytic subunit, mitochondrial
Name:Acetolactate synthase catalytic subunit, mitochondrial
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:74947.98
Organism:Saccharomyces cerevisiae
Description:ChEMBL_934102
Residue:687
Sequence:
MIRQSTLKNFAIKRCFQHIAYRNTPAMRSVALAQRFYSSSSRYYSASPLPASKRPEPAPS
FNVDPLEQPAEPSKLAKKLRAEPDMDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILP
VYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFAD
GIPMVVFTGQVPTSAIGTDAFQEADVVGISRSCTKWNVMVKSVEELPLRINEAFEIATSG
RPGPVLVDLPKDVTAAILRNPIPTKTTLPSNALNQLTSRAQDEFVMQSINKAADLINLAK
KPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATA
NLAVQNADLIIAVGARFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQ
IAVEGDATTNLGKMMSKIFPVKERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKL
SKVANDTGRHVIVTTGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKP
ESLVIDIDGDASFNMTLTELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQ
LNPDFIKLAEAMGLKGLRVKKQEELDAKLKEFVSTKGPVLLEVEVDKKVPVLPMVAGGSG
LDEFINFDPEVERQQTELRHKRTGGKH
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50424588
NameBDBM50424588
Synonyms:SULFOMETURON METHYL
TypeSmall organic molecule
Emp. Form.C15H16N4O5S
Mol. Mass.364.376
SMILESCOC(=O)c1ccccc1S(=O)(=O)NC(=O)Nc1nc(C)cc(C)n1
Structure
n/a