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Target
Beta-galactosidase
Ligand
BDBM50358321
Substrate
n/a
Meas. Tech.
ChEMBL_943698 (CHEMBL2344842)
Ki
300±n/a nM
Citation
 Boyd, RE; Lee, G; Rybczynski, P; Benjamin, ER; Khanna, R; Wustman, BA; Valenzano, KJ Pharmacological chaperones as therapeutics for lysosomal storage diseases. J Med Chem 56:2705-25 (2013) [PubMed]  Article 
Target
Name:
Beta-galactosidase
Synonyms:
Acid beta-galactosidase | BGAL_HUMAN | ELNR1 | Elastin receptor 1 | GLB1 | Lactase
Type:
PROTEIN
Mol. Mass.:
76074.43
Organism:
Homo sapiens (Human)
Description:
ChEMBL_215886
Residue:
677
Sequence:
MPGFLVRILPLLLVLLLLGPTRGLRNATQRMFEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGPLINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGPIPPSTPKFAYGKVTLEKLKTVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDRAYVAVDGIPQGVLERNNVITLNITGKAGATLDLLVENMGRVNYGAYINDFKGLVSNLTLSSNILTDWTIFPLDTEDAVRSHLGGWGHRDSGHHDEAWAHNSSNYTLPAFYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPNTITVLELEWAPCSSDDPELCAVTFVDRPVIGSSVTYDHPSKPVEKRLMPPPPQKNKDSWLDHV
  
Inhibitor
Name:
BDBM50358321
Synonyms:
CHEMBL1922579 | CHEMBL1922581
Type:
Small organic molecule
Emp. Form.:
C15H29NO4
Mol. Mass.:
287.3951
SMILES:
CCCCCCCCN[C@@H]1C=C(CO)[C@H](O)[C@H](O)[C@H]1O |r,t:10|
Structure:
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