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Target
Proteasome subunit beta type-1
Ligand
BDBM50434767
Substrate
n/a
Meas. Tech.
ChEMBL_962204 (CHEMBL2388792)
Ki
4420±n/a nM
Citation
 Micale, N; Ettari, R; Lavecchia, A; Di Giovanni, C; Scarbaci, K; Troiano, V; Grasso, S; Novellino, E; Schirmeister, T; Zappalà, M Development of peptidomimetic boronates as proteasome inhibitors. Eur J Med Chem 64:23-34 (2013) [PubMed]  Article 
Target
Name:
Proteasome subunit beta type-1
Synonyms:
PSB1_HUMAN | PSC5 | PSMB1 | Proteasome component C5 | Proteasome subunit beta type-1/beta type-5
Type:
PROTEIN
Mol. Mass.:
26493.62
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1366691
Residue:
241
Sequence:
MLSSTAMYSAPGRDLGMEPHRAAGPLQLRFSPYVFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLSLDRAMRLVKDVFISAAERDVYTGDALRICIVTKEGIREETVSLRKD
  
Inhibitor
Name:
BDBM50434767
Synonyms:
CHEMBL2385811
Type:
Small organic molecule
Emp. Form.:
C16H28BN3O4
Mol. Mass.:
337.222
SMILES:
CCN(CC)c1ccn(CC(=O)N[C@@H](CC(C)C)B(O)O)c(=O)c1 |r|
Structure:
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