Reaction Details Report a problem with these data
Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50374600
Substrate
n/a
Meas. Tech.
ChEMBL_976148 (CHEMBL2415797)
Ki
0.560000±n/a nM
Citation
 Bhat, R; Fishback, JA; Matsumoto, RR; Poupaert, JH; McCurdy, CR Structure activity relationship study of benzo[d]thiazol-2(3H)one baseds receptor ligands. Bioorg Med Chem Lett 23:5011-3 (2013) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein
Type:
Protein
Mol. Mass.:
25307.17
Organism:
Cavia porcellus (Guinea pig)
Description:
Q60492
Residue:
223
Sequence:
MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSKLIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50374600
Synonyms:
CHEMBL272899
Type:
Small organic molecule
Emp. Form.:
C18H26N2OS
Mol. Mass.:
318.477
SMILES:
CCCc1ccc2n(CCN3CCCCCC3)c(=O)sc2c1
Structure:
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