Reaction Details Report a problem with these data
Target
Virulence factor transcriptional regulator MvfR
Ligand
BDBM50106197
Substrate
n/a
Meas. Tech.
ChEMBL_980942 (CHEMBL2427495)
Kd
7600±n/a nM
Citation
 Zender, M; Klein, T; Henn, C; Kirsch, B; Maurer, CK; Kail, D; Ritter, C; Dolezal, O; Steinbach, A; Hartmann, RW Discovery and biophysical characterization of 2-amino-oxadiazoles as novel antagonists of PqsR, an important regulator of Pseudomonas aeruginosa virulence. J Med Chem 56:6761-74 (2013) [PubMed]  Article 
Target
Name:
Virulence factor transcriptional regulator MvfR
Synonyms:
Transcriptional regulator MvfR
Type:
PROTEIN
Mol. Mass.:
37217.11
Organism:
Pseudomonas aeruginosa PA14
Description:
ChEMBL_107649
Residue:
332
Sequence:
MPIHNLNHVNMFLQVIASGSISSAARILRKSHTAVSSAVSNLEIDLCVELVRRDGYKVEPTEQALRLIPYMRSLLNYQQLIGDIAFNLNKGPRNLRVLLDTAIPPSFCDTVSSVLLDDFNMVSLIRTSPADSLATIKQDNAEIDIAITIDEELKISRFNQCVLGYTKAFVVAHPQHPLCNASLHSIASLANYRQISLGSRSGQHSNLLRPVSDKVLFVENFDDMLRLVEAGVGWGIAPHYFVEERLRNGTLAVLSELYEPGGIDTKVYCYYNTALESERSFLRFLESARQRLRELGRQRFDDAPAWQPSIVETAQRRSGPKALAYRQRAAPE
  
Inhibitor
Name:
BDBM50106197
Synonyms:
3-Bromo-benzamide | CHEMBL122690
Type:
Small organic molecule
Emp. Form.:
C7H6BrNO
Mol. Mass.:
200.033
SMILES:
NC(=O)c1cccc(Br)c1
Structure:
Search PDB for entries with ligand similarity: