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TargetPPYR1
LigandBDBM50442570
Substrate/Competitorn/a
Meas. Tech.ChEMBL_990501
Ki>5000±n/a nM
Citation Keller, MKaske, MHolzammer, TBernhardt, GBuschauer, A Dimeric argininamide-type neuropeptide Y receptor antagonists: chiral discrimination between Y1 and Y4 receptors. Bioorg Med Chem21:6303-22 (2013) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
PPYR1
Name:Neuropeptide Y receptor type 4
Synonyms:NPY-Y4 | NPY4-R | Neuropeptide Y receptor type 4 | PP1 | Pancreatic polypeptide receptor 1
Type:Enzyme Catalytic Domain
Mol. Mass.:42207.58
Organism:Homo sapiens (Human)
Description:NPY-Y4 PPYR1 HUMAN::P50391
Residue:375
Sequence:
MNTSHLLALLLPKSPQGENRSKPLGTPYNFSEHCQDSVDVMVFIVTSYSIETVVGVLGNL
CLMCVTVRQKEKANVTNLLIANLAFSDFLMCLLCQPLTAVYTIMDYWIFGETLCKMSAFI
QCMSVTVSILSLVLVALERHQLIINPTGWKPSISQAYLGIVLIWVIACVLSLPFLANSIL
ENVFHKNHSKALEFLADKVVCTESWPLAHHRTIYTTFLLLFQYCLPLGFILVCYARIYRR
LQRQGRVFHKGTYSLRAGHMKQVNVVLVVMVVAFAVLWLPLHVFNSLEDWHHEAIPICHG
NLIFLVCHLLAMASTCVNPFIYGFLNTNFKKEIKALVLTCQQSAPLEESEHLPLSTVHTE
VSKGSLRLSGRSNPI
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50442570
NameBDBM50442570
Synonyms:CHEMBL2440900
TypeSmall organic molecule
Emp. Form.C38H51N11O6
Mol. Mass.757.8816
SMILESNCCNC(=O)CCC(=O)NCCNC(=O)NC(N)=NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(CNC(N)=O)cc1 |r,w:19.19|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a