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Target
DNA polymerase beta
Ligand
BDBM50448689
Substrate
n/a
Meas. Tech.
ChEMBL_1297299 (CHEMBL3132085)
Ki
5500±n/a nM
Citation
 Mizushina, Y; Suzuki-Fukudome, H; Takeuchi, T; Takemoto, K; Kuriyama, I; Yoshida, H; Kamisuki, S; Sugawara, F Formosusin A, a novel specific inhibitor of mammalian DNA polymeraseß from the fungus Paecilomyces formosus. Bioorg Med Chem 22:1070-6 (2014) [PubMed]  Article 
Target
Name:
DNA polymerase beta
Synonyms:
DNA Polymerase beta | DPOLB_RAT | Polb
Type:
PROTEIN
Mol. Mass.:
38334.34
Organism:
Rattus norvegicus
Description:
ChEMBL_1361926
Residue:
335
Sequence:
MSKRKAPQETLNGGITDMLVELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVTGIGPSAARKLVDEGIKTLEDLRKNEDKLNHHQRIGLKYFEDFEKRIPREEMLQMQDIVLNEVKKLDPEYIATVCGSFRRGAESSGDMDVLLTHPNFTSESSKQPKLLHRVVEQLQKVRFITDTLSKGETKFMGVCQLPSENDENEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEQDIFDYIQWRYREPKDRSE
  
Inhibitor
Name:
BDBM50448689
Synonyms:
CHEMBL3127730
Type:
Small organic molecule
Emp. Form.:
C17H25NO3
Mol. Mass.:
291.3853
SMILES:
CCCC[C@@H](O)\C=C(/C)\C=C\C=C/C(=O)N1CCCC1=O |r|
Structure:
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