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Target
CD44 antigen
Ligand
BDBM50008917
Substrate
n/a
Meas. Tech.
ChEMBL_1337580 (CHEMBL3242489)
Kd
500000±n/a nM
Citation
 Liu, LK; Finzel, BC Fragment-based identification of an inducible binding site on cell surface receptor CD44 for the design of protein-carbohydrate interaction inhibitors. J Med Chem 57:2714-25 (2014) [PubMed]  Article 
Target
Name:
CD44 antigen
Synonyms:
CD44_MOUSE | CD_antigen=CD44 | Cd44 | ECMR-III | Extracellular matrix receptor III | GP90 lymphocyte homing/adhesion receptor | HUTCH-I | Hermes antigen | Hyaluronate receptor | Ly-24
Type:
PROTEIN
Mol. Mass.:
85579.86
Organism:
Mus musculus
Description:
ChEMBL_108281
Residue:
778
Sequence:
MDKFWWHTAWGLCLLQLSLAHQQIDLNVTCRYAGVFHVEKNGRYSISRTEAADLCQAFNSTLPTMDQMKLALSKGFETCRYGFIEGNVVIPRIHPNAICAANHTGVYILVTSNTSHYDTYCFNASAPPEEDCTSVTDLPNSFDGPVTITIVNRDGTRYSKKGEYRTHQEDIDASNIIDDDVSSGSTIEKSTPEGYILHTYLPTEQPTGDQDDSFFIRSTLATIASTVHSKSHAAAQKQNNWIWSWFGNSQSTTQTQEPTTSATTALMTTPETPPKRQEAQNWFSWLFQPSESKSHLHTTTKMPGTESNTNPTGWEPNEENEDETDTYPSFSGSGIDDDEDFISSTIATTPRVSARTEDNQDWTQWKPNHSNPEVLLQTTTRMADIDRISTSAHGENWTPEPQPPFNNHEYQDEEETPHATSTTPNSTAEAAATQQETWFQNGWQGKNPPTPSEDSHVTEGTTASAHNNHPSQRITTQSQEDVSWTDFFDPISHPMGQGHQTESKDTDSSHSTTLQPTAAPNTHLVEDLNRTGPLSVTTPQSHSQNFSTLHGEPEEDENYPTTSILPSSTKSSAKDARRGGSLPTDTTTSVEGYTFQYPDTMENGTLFPVTPAKTEVFGETEVTLATDSNVNVDGSLPGDRDSSKDSRGSSRTVTHGSELAGHSSANQDSGVTTTSGPMRRPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKKLVINGGNGTVEDRKPSELNGEASKSQEMVHLVNKEPSETPDQCMTADETRNLQSVDMKIGV
  
Inhibitor
Name:
BDBM50008917
Synonyms:
CHEMBL3237627
Type:
Small organic molecule
Emp. Form.:
C14H18N4
Mol. Mass.:
242.3195
SMILES:
Cc1nc[nH]c1CN1CCc2cccc(N)c2C1
Structure:
Search PDB for entries with ligand similarity: