Reaction Details Report a problem with these data
Target
Glandular kallikrein
Ligand
BDBM50009967
Substrate
n/a
Meas. Tech.
ChEMBL_1342913 (CHEMBL3259188)
Ki
15300±n/a nM
Citation
 Tidwell, RR; Geratz, JD; Dann, O; Volz, G; Zeh, D; Loewe, H Diarylamidine derivatives with one or both of the aryl moieties consisting of an indole or indole-like ring. Inhibitors of arginine-specific esteroproteases. J Med Chem 21:613-23 (1978) [PubMed]  Article 
Target
Name:
Glandular kallikrein
Synonyms:
KLK_PIG | Tissue kallikrein
Type:
PROTEIN
Mol. Mass.:
26710.38
Organism:
Sus scrofa
Description:
ChEMBL_108296
Residue:
242
Sequence:
APPIQSRIIGGRECEKNSHPWQVAIYHYSSFQCGGVLVNPKWVLTAAHCKNDNYEVWLGRHNLFENENTAQFFGVTADFPHPGFNLSLLKHTKADGKDYSHDLMLLRLQSPAKITDAVKVLELPTQEPELGSTCEASGWGSIEPGPDFEFPDEIQCVQLTLLQNTFCAAHPKVTESMLCAGYLPGGKDTCMGDSGGPLICNGMWQGITSWGHTPCGSANKPSIYTKLIFYLDWINDTITENP
  
Inhibitor
Name:
BDBM50009967
Synonyms:
CHEMBL417907
Type:
Small organic molecule
Emp. Form.:
C22H18N8
Mol. Mass.:
394.4319
SMILES:
NC(=N)c1ccc2[nH]c(nc2c1)-c1ccc(cc1)-c1nc2cc(ccc2[nH]1)C(N)=N
Structure:
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