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Target
Histidine decarboxylase
Ligand
BDBM50010139
Substrate
n/a
Meas. Tech.
ChEMBL_1344422 (CHEMBL3258372)
Ki
1800±n/a nM
Citation
 Kelley, JL; Miller, CA; White, HL Inhibition of histidine decarboxylase. Derivatives of histidine. J Med Chem 20:506-9 (1977) [PubMed]  Article 
Target
Name:
Histidine decarboxylase
Synonyms:
DCHS_RAT | Hdc
Type:
PROTEIN
Mol. Mass.:
73643.55
Organism:
Rattus norvegicus
Description:
ChEMBL_108298
Residue:
656
Sequence:
MMEPSEYHEYQARGKEMVDYICQYLSTVRERQVTPNVKPGYLRAQIPSSAPEEPDSWDSIFGDIEQIIMPGVVHWQSPHMHAYYPALTSWPSLLGDMLADAINCLGFTWASSPACTELEMNIMDWLAKMLGLPDFFLHHHPSSQGGGVLQRTVSESTLIALLAARKNKILEMKAHEPNADESSLNARLVAYASDQAHSSVEKAGLISLVKIKFLPVDDNFSLRGEALQKAIEEDKQQGLVPVFVCATLGTTGVCAFDKLSELGPICAREGLWLHVDAAYAGTAFLRPELRGFLKGIEYADSFTFNPSKWMMVHFDCTGFWVKDKYKLQQTFSVNPIYLRHANSGVATDFMHWQIPLSRRFRSIKLWFVIRSFGVKNLQAHVRHGTDMAKYFESLVRSDPVFEIPAERHLGLVVFRLKGPNCLTESVLKEIAKTGQVFLIPATIQDKLIIRFTVTSQFTTKDDILRDWNLIREAANLVLSQHCTSQPSPRAKNLIPPPVTRDSKDLTNGLSLESVNEGGDDPVQVRKIFRLPGDSLETTMDPFDDCFSEEASDTTKHKLSSFLFSYLSVQNKKKTMRSLSCNSMPMSAQKSPPPDASVKHGGFFRARIFSGFPEEMMMMKKGGFKKLIKFYSVPSFPECSSQCGTLQLPCCPLQAMV
  
Inhibitor
Name:
BDBM50010139
Synonyms:
CHEMBL54664 | L-Histidine Methyl Ester
Type:
Small organic molecule
Emp. Form.:
C7H11N3O2
Mol. Mass.:
169.1811
SMILES:
COC(=O)[C@@H](N)Cc1c[nH]cn1 |r|
Structure:
Search PDB for entries with ligand similarity: