Reaction Details Report a problem with these data
Target
Glandular kallikrein
Ligand
BDBM50016533
Substrate
n/a
Meas. Tech.
ChEMBL_1354676 (CHEMBL3281101)
Ki
5500±n/a nM
Citation
 Geratz, JD; Cheng, MC; Tidwell, RR Novel bis(benzamidino) compounds with an aromatic central link. Inhibitors of thrombin, pancreatic kallikrein, trypsin, and complement. J Med Chem 19:634-9 (1976) [PubMed]  Article 
Target
Name:
Glandular kallikrein
Synonyms:
KLK_PIG | Tissue kallikrein
Type:
PROTEIN
Mol. Mass.:
26710.38
Organism:
Sus scrofa
Description:
ChEMBL_108296
Residue:
242
Sequence:
APPIQSRIIGGRECEKNSHPWQVAIYHYSSFQCGGVLVNPKWVLTAAHCKNDNYEVWLGRHNLFENENTAQFFGVTADFPHPGFNLSLLKHTKADGKDYSHDLMLLRLQSPAKITDAVKVLELPTQEPELGSTCEASGWGSIEPGPDFEFPDEIQCVQLTLLQNTFCAAHPKVTESMLCAGYLPGGKDTCMGDSGGPLICNGMWQGITSWGHTPCGSANKPSIYTKLIFYLDWINDTITENP
  
Inhibitor
Name:
BDBM50016533
Synonyms:
CHEMBL3277930
Type:
Small organic molecule
Emp. Form.:
C26H25ClN4O2
Mol. Mass.:
460.955
SMILES:
Cl.NC(=N)c1cccc(OCc2ccc3cc(COc4cccc(c4)C(N)=N)ccc3c2)c1
Structure:
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