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Target
Accessory gene regulator protein A
Ligand
BDBM50312649
Substrate
n/a
Meas. Tech.
ChEMBL_1366621 (CHEMBL3296715)
IC50
37800±n/a nM
Citation
 Figueroa, M; Jarmusch, AK; Raja, HA; El-Elimat, T; Kavanaugh, JS; Horswill, AR; Cooks, RG; Cech, NB; Oberlies, NH Polyhydroxyanthraquinones as quorum sensing inhibitors from the guttates of Penicillium restrictum and their analysis by desorption electrospray ionization mass spectrometry. J Nat Prod 77:1351-8 (2014) [PubMed]  Article 
Target
Name:
Accessory gene regulator protein A
Synonyms:
AGRA_STAAU | agr | agrA
Type:
PROTEIN
Mol. Mass.:
27903.57
Organism:
Staphylococcus aureus
Description:
ChEMBL_1366621
Residue:
238
Sequence:
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDPVGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIMFFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI
  
Inhibitor
Name:
BDBM50312649
Synonyms:
6-chloro-4,5,7-trihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid | CHEMBL1089732
Type:
Small organic molecule
Emp. Form.:
C15H7ClO7
Mol. Mass.:
334.665
SMILES:
OC(=O)c1cc(O)c2C(=O)c3c(O)c(Cl)c(O)cc3C(=O)c2c1
Structure:
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