Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 2A
Ligand
BDBM30853
Substrate
n/a
Meas. Tech.
ChEMBL_1442874 (CHEMBL3377152)
EC50
2.6±n/a nM
Citation
 Blough, BE; Landavazo, A; Partilla, JS; Decker, AM; Page, KM; Baumann, MH; Rothman, RB Alpha-ethyltryptamines as dual dopamine-serotonin releasers. Bioorg Med Chem Lett 24:4754-8 (2014) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 2A
Synonyms:
5-HT-2 | 5-HT-2A | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT-2A) | 5-hydroxytryptamine receptor 2A (5HT-2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_HUMAN | HTR2 | HTR2A | Serotonin receptor 2A
Type:
undefined
Mol. Mass.:
52607.65
Organism:
Homo sapiens (Human)
Description:
P28223
Residue:
471
Sequence:
MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV
  
Inhibitor
Name:
BDBM30853
Synonyms:
2-(5-fluoranyl-1H-indol-3-yl)ethanamine;hydrochloride | 2-(5-fluoro-1H-indol-3-yl)ethanamine;hydrochloride | 2-(5-fluoro-1H-indol-3-yl)ethylamine;hydrochloride | 5-F-T | CHEMBL275628 | MLS000047815 | SMR000033820 | cid_197774
Type:
Small organic molecule
Emp. Form.:
C10H11FN2
Mol. Mass.:
178.2061
SMILES:
NCCc1c[nH]c2ccc(F)cc12
Structure:
Search PDB for entries with ligand similarity: