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Target
Transcription factor Jun
Ligand
BDBM50044555
Substrate
n/a
Meas. Tech.
ChEMBL_1458007 (CHEMBL3367181)
IC50
60000±n/a nM
Citation
 Ye, N; Ding, Y; Wild, C; Shen, Q; Zhou, J Small molecule inhibitors targeting activator protein 1 (AP-1). J Med Chem 57:6930-48 (2014) [PubMed]  Article 
Target
Name:
Transcription factor Jun
Synonyms:
AP1 | Activator protein 1 | JUN_RAT | Jun | Proto-oncogene c-Jun | Rjg-9 | Transcription factor AP-1 | V-jun avian sarcoma virus 17 oncogene homolog
Type:
PROTEIN
Mol. Mass.:
36008.54
Organism:
Rattus norvegicus
Description:
ChEMBL_109493
Residue:
334
Sequence:
MTAKMETTFYDDALNASFLQSESGAYGYSNPKILKQSMTLNLADPVGNLKPHLRAKNSDLLTSPDVGLLKLASPELERLIIQSSNGHITTTPTPTQFLCPKNVTDEQEGFAEGFVRALAELHSQNTLPSVTSAAQPVSGAGMVAPAVASVAGAGGGGGYSASLHSEPPVYANLSNFNPGALSSGGGAPSYGATGLAFPSQPQQQQQPPQPPHHLPQQIPVQHPRLQALKEEPQTVPEMPGETPPLSPIDMESQERIKAERKRMRNRIAASKCRKRKLERIARLEEKVKTLKAQNSELASTANMLREQVAQLKQKVMNHVNSGCQLMLTQQLQTF
  
Inhibitor
Name:
BDBM50044555
Synonyms:
CHEMBL3341957
Type:
Small organic molecule
Emp. Form.:
C18H14O6
Mol. Mass.:
326.3002
SMILES:
CCCc1c(C(O)=O)c(O)cc2C(=O)c3cccc(O)c3C(=O)c12
Structure:
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