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Target
Peptidyl-prolyl cis-trans isomerase FKBP1B
Ligand
BDBM36609
Substrate
n/a
Meas. Tech.
ChEMBL_1458980 (CHEMBL3369573)
Kd
0.200000±n/a nM
Citation
 Gibbs, AC Elements and modulation of functional dynamics. J Med Chem 57:7819-37 (2014) [PubMed]  Article 
Target
Name:
Peptidyl-prolyl cis-trans isomerase FKBP1B
Synonyms:
12.6 kDa FKBP | FK506-binding protein 1B | FKB1B_HUMAN | FKBP-12.6 | FKBP-1B | FKBP12.6 | FKBP1B | FKBP1L | FKBP9 | Immunophilin FKBP12.6 | OTK4 | PPIase FKBP1B | Peptidyl-prolyl cis-trans isomerase FKBP1B | Rotamase | h-FKBP-12 | mTOR/FKBP12A/FKBP12B
Type:
PROTEIN
Mol. Mass.:
11785.40
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1458980
Residue:
108
Sequence:
MGVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGAAQMSLGQRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLNLE
  
Inhibitor
Name:
BDBM36609
Synonyms:
Rapamycin C-7, analog 4 | SIROLIMUS | US11603377, Compound Ramycin
Type:
Small organic molecule
Emp. Form.:
C51H79NO13
Mol. Mass.:
914.1719
SMILES:
CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O |c:14,33,t:29,31|
Structure:
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