Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50045595
Substrate
n/a
Meas. Tech.
ChEMBL_1454505 (CHEMBL3365947)
Ki
978±n/a nM
Citation
 Toti, KS; Moss, SM; Paoletta, S; Gao, ZG; Jacobson, KA; Van Calenbergh, S Synthesis and evaluation of N6-substituted apioadenosines as potential adenosine A3 receptor modulators. Bioorg Med Chem 22:4257-68 (2014) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50045595
Synonyms:
CHEMBL3311505
Type:
Small organic molecule
Emp. Form.:
C18H20ClN5O5
Mol. Mass.:
421.835
SMILES:
COc1ccc(Cl)cc1CNc1ncnc2n(cnc12)[C@@H]1OC[C@](O)(CO)[C@H]1O |r|
Structure:
Search PDB for entries with ligand similarity: