Reaction Details Report a problem with these data
Target
Deoxyribonuclease-1
Ligand
BDBM50052802
Substrate
n/a
Meas. Tech.
ChEMBL_1457550 (CHEMBL3368168)
IC50
350±n/a nM
Citation
 Kolarevic, A; Yancheva, D; Kocic, G; Smelcerovic, A Deoxyribonuclease inhibitors. Eur J Med Chem 88:101-11 (2014) [PubMed]  Article 
Target
Name:
Deoxyribonuclease-1
Synonyms:
DNAS1_HUMAN | DNASE1 | DNL1 | DNL1 | DNase I | DRNI | Deoxyribonuclease I | Deoxyribonuclease-1 | INN=Dornase alfa
Type:
PROTEIN
Mol. Mass.:
31422.78
Organism:
Homo sapiens (Human)
Description:
ChEMBL_109543
Residue:
282
Sequence:
MRGMKLLGALLALAALLQGAVSLKIAAFNIQTFGETKMSNATLVSYIVQILSRYDIALVQEVRDSHLTAVGKLLDNLNQDAPDTYHYVVSEPLGRNSYKERYLFVYRPDQVSAVDSYYYDDGCEPCGNDTFNREPAIVRFFSRFTEVREFAIVPLHAAPGDAVAEIDALYDVYLDVQEKWGLEDVMLMGDFNAGCSYVRPSQWSSIRLWTSPTFQWLIPDSADTTATPTHCAYDRIVVAGMLLRGAVVPDSALPFNFQAAYGLSDQLAQAISDHYPVEVMLK
  
Inhibitor
Name:
BDBM50052802
Synonyms:
CHEBI:77181 | CRYSTAL VIOLET | Crystal violet (15) | Hexamethyl pararosaniline
Type:
Small organic molecule
Emp. Form.:
C25H30N3
Mol. Mass.:
372.5253
SMILES:
[#6]-[#7](-[#6])-c1ccc(cc1)-[#6](=[#6]-1\[#6]=[#6]/[#6](/[#6]=[#6]-1)=[#7+](\[#6])-[#6])\c1ccc(cc1)-[#7](-[#6])-[#6] |c:12,15|
Structure:
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