Reaction Details Report a problem with these data
Target
Succinate dehydrogenase cytochrome b560 subunit, mitochondrial
Ligand
BDBM50079610
Substrate
n/a
Meas. Tech.
ChEMBL_1472195 (CHEMBL3418826)
IC50
11±n/a nM
Citation
 Xiong, L; Zhu, XL; Shen, YQ; Wishwajith, WK; Li, K; Yang, GF Discovery of N-benzoxazol-5-yl-pyrazole-4-carboxamides as nanomolar SQR inhibitors. Eur J Med Chem 95:424-34 (2015) [PubMed]  Article 
Target
Name:
Succinate dehydrogenase cytochrome b560 subunit, mitochondrial
Synonyms:
C560_PIG | CYBL | SDHC | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial | Succinate-ubiquinone oxidoreductase cytochrome B large subunit
Type:
PROTEIN
Mol. Mass.:
18529.95
Organism:
Sus scrofa
Description:
ChEMBL_106708
Residue:
169
Sequence:
MAALLLRHVGRHCLRAHLSPQLCIRNAVPLGTTAKEEMERFWNKNLGSNRPLSPHITIYRWSLPMAMSICHRGTGIALSAGVSLFGLSALLLPGNFESHLELVKSLCLGPTLIYTAKFGIVFPLMYHTWNGIRHLIWDLGKGLTIPQLTQSGVVVLILTVLSSVGLAAM
  
Inhibitor
Name:
BDBM50079610
Synonyms:
CHEMBL3417782
Type:
Small organic molecule
Emp. Form.:
C21H15F5N4O3S
Mol. Mass.:
498.426
SMILES:
Cn1cc(C(=O)Nc2ccc3oc(SCc4ccc(OC(F)(F)F)cc4)nc3c2)c(n1)C(F)F
Structure:
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