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Target
Low molecular weight phosphotyrosine protein phosphatase
Ligand
BDBM50096253
Substrate
n/a
Meas. Tech.
ChEMBL_1506094 (CHEMBL3595960)
Ki
124000±n/a nM
Citation
 Fonseca, EM; Trivella, DB; Scorsato, V; Dias, MP; Bazzo, NL; Mandapati, KR; de Oliveira, FL; Ferreira-Halder, CV; Pilli, RA; Miranda, PC; Aparicio, R Crystal structures of the apo form and a complex of human LMW-PTP with a phosphonic acid provide new evidence of a secondary site potentially related to the anchorage of natural substrates. Bioorg Med Chem 23:4462-71 (2015) [PubMed]  Article 
Target
Name:
Low molecular weight phosphotyrosine protein phosphatase
Synonyms:
Acp1 | LMW-PTP | LMW-PTPase | Low molecular weight cytosolic acid phosphatase | Low molecular weight phosphotyrosine protein phosphatase | PPAC_MOUSE
Type:
PROTEIN
Mol. Mass.:
18192.04
Organism:
Mus musculus
Description:
ChEMBL_109834
Residue:
158
Sequence:
MAEVGSKSVLFVCLGNICRSPIAEAVFRKLVTDEKVSDNWRIDSAATSTYEVGNPPDYRGQNCMRKHGIHMQHIARQITKEDFATFDYILCMDESNLRDLNRKSNQVKNCKAKIELLGSYDPQKQLIIEDPYYGNDSDFEVVYQQCLRCCKAFLEKTY
  
Inhibitor
Name:
BDBM50096253
Synonyms:
CHEMBL3593255
Type:
Small organic molecule
Emp. Form.:
C7H8NO5P
Mol. Mass.:
217.1159
SMILES:
OP(O)(=O)Cc1ccc(cc1)[N+]([O-])=O
Structure:
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