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TargetCytochrome P450 2A13
LigandBDBM50008072
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1486539
Ki 1400±n/a nM
Citation Stephens, ESWalsh, AAScott, EE Evaluation of inhibition selectivity for human cytochrome P450 2A enzymes. Drug Metab Dispos40:1797-802 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Cytochrome P450 2A13
Name:Cytochrome P450 2A13 (CYP2A13)
Synonyms:CYPIIA13
Type:Protein
Mol. Mass.:56702.46
Organism:Homo sapiens (Human)
Description:Q16696
Residue:494
Sequence:
MLASGLLLVTLLACLTVMVLMSVWRQRKSRGKLPPGPTPLPFIGNYLQLNTEQMYNSLMK
ISERYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSN
GERAKQLRRFSIATLRGFGVGKRGIEERIQEEAGFLIDALRGTHGANIDPTFFLSRTVSN
VISSIVFGDRFDYEDKEFLSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLPGPQQQAFKE
LQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQEEEKNPNTEFYLKNLVMTTLNLFF
AGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYTEAVIHEIQ
RFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQHFLDKK
GQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFKSPQSPKDIDVSPKHVGF
ATIPRNYTMSFLPR
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50008072
NameBDBM50008072
Synonyms:(+)-pilocarpine | (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one | (3S,4R)-3-ethyldihydro-4-((1-methyl-1H-imidazol-5-yl)methyl)-2(3H)-furanone | (3S-cis)-3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-2(3H)-furanone | CHEMBL550 | ISOPTO CARPINE | PILOCARPINE | PILOCARPINE HYDROCHLORIDE
TypeSmall organic molecule
Emp. Form.C11H16N2O2
Mol. Mass.208.2569
SMILESCC[C@H]1[C@@H](Cc2cncn2C)COC1=O |r|
Structure
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n/a