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Target
Cannabinoid receptor 1
Ligand
BDBM50116910
Substrate
n/a
Meas. Tech.
ChEMBL_1516108 (CHEMBL3615751)
Ki
>5000±n/a nM
Citation
 Ragusa, G; Gómez-Cañas, M; Morales, P; Hurst, DP; Deligia, F; Pazos, R; Pinna, GA; Fernández-Ruiz, J; Goya, P; Reggio, PH; Jagerovic, N; García-Arencibia, M; Murineddu, G Synthesis, pharmacological evaluation and docking studies of pyrrole structure-based CB2 receptor antagonists. Eur J Med Chem 101:651-67 (2015) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50116910
Synonyms:
CHEMBL3613102
Type:
Small organic molecule
Emp. Form.:
C30H33ClN2O
Mol. Mass.:
473.049
SMILES:
Cc1ccc(Cn2cc(cc2-c2ccc(Cl)c(C)c2)C(=O)NC23CC4CC(CC(C4)C2)C3)cc1 |TLB:29:24:31:28.30.27,29:28:31:23.24.25,THB:27:26:23:29.28.30,27:28:23:31.25.26|
Structure:
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