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Target
Kappa-type opioid receptor
Ligand
BDBM50123595
Substrate
n/a
Meas. Tech.
ChEMBL_1521810 (CHEMBL3626670)
Ki
210±n/a nM
Citation
 Lee, DY; Deng, G; Ma, Z; Xu, W; Yang, L; Liu, J; Dai, R; Liu-Chen, LY Synthesis and biological evaluation of 2-alkyl-2-methoxymethyl-salvinorin ethers as selectiveż-opioid receptor agonists. Bioorg Med Chem Lett 25:4689-92 (2015) [PubMed]  Article 
Target
Name:
Kappa-type opioid receptor
Synonyms:
K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42648.76
Organism:
Homo sapiens (Human)
Description:
P41145
Residue:
380
Sequence:
MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRVRNTVQDPAYLRDIDGMNKPV
  
Inhibitor
Name:
BDBM50123595
Synonyms:
CHEMBL3622710
Type:
Small organic molecule
Emp. Form.:
C25H34O7
Mol. Mass.:
446.5333
SMILES:
[H][C@]12CC[C@@]3(C)[C@@H](C[C@](CC)(COC)C(=O)[C@]3([H])[C@@]1(C)C[C@H](OC2=O)c1ccoc1)C(=O)OC |r|
Structure:
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