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Target
Carbonic anhydrase 7
Ligand
BDBM50259746
Substrate
n/a
Meas. Tech.
ChEMBL_1523556 (CHEMBL3631204)
Ki
620±n/a nM
Citation
 Maresca, A; Akyuz, G; Osman, SM; AlOthman, Z; Supuran, CT Inhibition of mammalian carbonic anhydrase isoforms I-XIV with a series of phenolic acid esters. Bioorg Med Chem 23:7181-8 (2015) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 7
Synonyms:
CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII)
Type:
Enzyme
Mol. Mass.:
29664.11
Organism:
Homo sapiens (Human)
Description:
Human cloned isozyme.
Residue:
264
Sequence:
MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNNFRPPQPLKGRVVKASFRA
  
Inhibitor
Name:
BDBM50259746
Synonyms:
(4-Hydroxyphenyl)ethyl trans-ferulate | CHEMBL481245 | p-Hydroxyphenethyl trans-ferulate (18) | p-hydroxyphenethyl trans-ferulate
Type:
Small organic molecule
Emp. Form.:
C18H18O5
Mol. Mass.:
314.3325
SMILES:
COc1cc(\C=C\C(=O)OCCc2ccc(O)cc2)ccc1O
Structure:
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