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Target
Proteinase-activated receptor 2
Ligand
BDBM50134201
Substrate
n/a
Meas. Tech.
ChEBML_1539846
IC50
5000000±n/a nM
Citation
 Cho, NC; Cha, JH; Kim, H; Kwak, J; Kim, D; Seo, SH; Shin, JS; Kim, T; Park, KD; Lee, J; No, KT; Kim, YK; Lee, KT; Pae, AN Discovery of 2-aryloxy-4-amino-quinazoline derivatives as novel protease-activated receptor 2 (PAR2) antagonists. Bioorg Med Chem 23:7717-27 (2015) [PubMed]  Article 
Target
Name:
Proteinase-activated receptor 2
Synonyms:
F2RL1 | GPR11 | PAR2 | PAR2_HUMAN
Type:
PROTEIN
Mol. Mass.:
44152.54
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1497756
Residue:
397
Sequence:
MRSPSAAWLLGAAILLAASLSCSGTIQGTNRSSKGRSLIGKVDGTSHVTGKGVTVETVFSVDEFSASVLTGKLTTVFLPIVYTIVFVVGLPSNGMALWVFLFRTKKKHPAVIYMANLALADLLSVIWFPLKIAYHIHGNNWIYGEALCNVLIGFFYGNMYCSILFMTCLSVQRYWVIVNPMGHSRKKANIAIGISLAIWLLILLVTIPLYVVKQTIFIPALNITTCHDVLPEQLLVGDMFNYFLSLAIGVFLFPAFLTASAYVLMIRMLRSSAMDENSEKKRKRAIKLIVTVLAMYLICFTPSNLLLVVHYFLIKSQGQSHVYALYIVALCLSTLNSCIDPFVYYFVSHDFRDHAKNALLCRSVRTVKQMQVSLTSKKHSRKSSSYSSSSTTVKTSY
  
Inhibitor
Name:
BDBM50134201
Synonyms:
CHEMBL3734977
Type:
Small organic molecule
Emp. Form.:
C15H29N3O2
Mol. Mass.:
283.4097
SMILES:
CC(C)CC(=O)N1CCN(CC1)C(=O)CCCCCN
Structure:
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