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Target
Lymphocyte antigen 96
Ligand
BDBM50157621
Substrate
n/a
Meas. Tech.
ChEMBL_1568720 (CHEMBL3791885)
KOFF
1.220000 s-1
Citation
 Chen, G; Zhang, Y; Liu, X; Fang, Q; Wang, Z; Fu, L; Liu, Z; Wang, Y; Zhao, Y; Li, X; Liang, G Discovery of a New Inhibitor of Myeloid Differentiation 2 from Cinnamamide Derivatives with Anti-Inflammatory Activity in Sepsis and Acute Lung Injury. J Med Chem 59:2436-51 (2016) [PubMed]  Article 
Target
Name:
Lymphocyte antigen 96
Synonyms:
ESOP-1 | ESOP1 | ESOP1 | LY96 | LY96_HUMAN | Ly-96 | Lymphocyte antigen 96 | MD2 | Protein MD-2 | TLR4-MD2
Type:
PROTEIN
Mol. Mass.:
18551.39
Organism:
Homo sapiens (Human)
Description:
ChEMBL_107939
Residue:
160
Sequence:
MLPFLFFSTLFSSIFTEAQKQYWVCNSSDASISYTYCDKMQYPISINVNPCIELKRSKGLLHIFYIPRRDLKQLYFNLYITVNTMNLPKRKEVICRGSDDDYSFCRALKGETVNTTISFSFKGIKFSKGKYKCVVEAISGSPEEMLFCLEFVILHQPNSN
  
Inhibitor
Name:
BDBM50157621
Synonyms:
CHEMBL3787558
Type:
Small organic molecule
Emp. Form.:
C24H28N2O6
Mol. Mass.:
440.4889
SMILES:
COc1ccc(\C=C\C(=O)NCCNC(=O)\C=C\c2ccc(OC)cc2OC)c(OC)c1
Structure:
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