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Target
Death-associated protein kinase 2
Ligand
BDBM50166254
Substrate
n/a
Meas. Tech.
ChEMBL_1575379 (CHEMBL3802097)
IC50
570±n/a nM
Citation
 Jung, ME; Byun, BJ; Kim, HM; Lee, JY; Park, JH; Lee, N; Son, YH; Choi, SU; Yang, KM; Kim, SJ; Lee, K; Kim, YC; Choi, G Discovery of indirubin derivatives as new class of DRAK2 inhibitors from high throughput screening. Bioorg Med Chem Lett 26:2719-23 (2016) [PubMed]  Article 
Target
Name:
Death-associated protein kinase 2
Synonyms:
DAP kinase 2 | DAP-kinase-related protein 1 | DAPK2 | DAPK2_HUMAN | DRP-1
Type:
PROTEIN
Mol. Mass.:
42900.09
Organism:
Homo sapiens (Human)
Description:
ChEMBL_774557
Residue:
370
Sequence:
MFQASMRSPNMEPFKQQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVSILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDNQQAMVRRESVVNLENFRKQYVRRRWKLSFSIVSLCNHLTRSLMKKVHLRPDEDLRNCESDTEEDIARRKALHPRRRSSTS
  
Inhibitor
Name:
BDBM50166254
Synonyms:
CHEMBL3797466
Type:
Small organic molecule
Emp. Form.:
C21H18N4O3
Mol. Mass.:
374.3926
SMILES:
[#6]\[#6](-[#6])=[#6]\[#6](=O)-[#7]-c1ccc2-[#7]-[#6](=O)\[#6](=[#6]3/[#7]-c4ccccc4/[#6]/3=[#7]\[#8])-c2c1
Structure:
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