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Target
D(2) dopamine receptor
Ligand
BDBM50171476
Substrate
n/a
Meas. Tech.
ChEMBL_1576957 (CHEMBL3806800)
IC50
35±n/a nM
Citation
 Yang, F; Jiang, X; Li, J; Wang, Y; Liu, Y; Bi, M; Wu, C; Zhao, Q; Chen, W; Yin, J; Zhang, J; Xie, Y; Hu, T; Xu, M; Guo, S; Wang, Z; He, Y; Shen, J Synthesis, structure-activity relationships, and biological evaluation of a series of benzamides as potential multireceptor antipsychotics. Bioorg Med Chem Lett 26:3141-7 (2016) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50171476
Synonyms:
CHEMBL3806224
Type:
Small organic molecule
Emp. Form.:
C22H26Cl3N3O2
Mol. Mass.:
470.82
SMILES:
CNC(=O)c1cc(OCCCCN2CCN(CC2)c2cccc(Cl)c2Cl)ccc1Cl
Structure:
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