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Target
Glucose-dependent insulinotropic receptor
Ligand
BDBM50172069
Substrate
n/a
Meas. Tech.
ChEMBL_1580706 (CHEMBL3811152)
EC50
400±n/a nM
Citation
 Ritter, K; Buning, C; Halland, N; Pöverlein, C; Schwink, L G Protein-Coupled Receptor 119 (GPR119) Agonists for the Treatment of Diabetes: Recent Progress and Prevailing Challenges. J Med Chem 59:3579-92 (2016) [PubMed]  Article 
Target
Name:
Glucose-dependent insulinotropic receptor
Synonyms:
G-protein coupled receptor 119 (GPR119) | GP119_HUMAN | GPR119 | Glucose-dependent insulinotropic receptor
Type:
Protein
Mol. Mass.:
36901.49
Organism:
Homo sapiens (Human)
Description:
Q8TDV5
Residue:
335
Sequence:
MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISGLLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLKIMSGFVAGACIAGLWLVSYLIGFLPLGIPMFQQTAYKGQCSFFAVFHPHFVLTLSCVGFFPAMLLFVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFKALRTVSVLIGSFALSWTPFLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKVLTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
  
Inhibitor
Name:
BDBM50172069
Synonyms:
CHEMBL3809616
Type:
Small organic molecule
Emp. Form.:
C21H28FN3O6S
Mol. Mass.:
469.527
SMILES:
C[C@H](OC1CCN(CC1)C(=O)OC(C)(C)C)c1nc(no1)-c1ccc(c(F)c1)S(C)(=O)=O |r|
Structure:
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