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Target
Glucose-dependent insulinotropic receptor
Ligand
BDBM50172072
Substrate
n/a
Meas. Tech.
ChEMBL_1580708 (CHEMBL3811154)
EC50
33±n/a nM
Citation
 Ritter, K; Buning, C; Halland, N; Pöverlein, C; Schwink, L G Protein-Coupled Receptor 119 (GPR119) Agonists for the Treatment of Diabetes: Recent Progress and Prevailing Challenges. J Med Chem 59:3579-92 (2016) [PubMed]  Article 
Target
Name:
Glucose-dependent insulinotropic receptor
Synonyms:
G-protein coupled receptor 119 (GPR119) | GP119_HUMAN | GPR119 | Glucose-dependent insulinotropic receptor
Type:
Protein
Mol. Mass.:
36901.49
Organism:
Homo sapiens (Human)
Description:
Q8TDV5
Residue:
335
Sequence:
MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISGLLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLKIMSGFVAGACIAGLWLVSYLIGFLPLGIPMFQQTAYKGQCSFFAVFHPHFVLTLSCVGFFPAMLLFVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFKALRTVSVLIGSFALSWTPFLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKVLTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
  
Inhibitor
Name:
BDBM50172072
Synonyms:
CHEMBL3809973
Type:
Small organic molecule
Emp. Form.:
C22H29FN4O2
Mol. Mass.:
400.4897
SMILES:
CC(C)c1noc(n1)N1CCC(CC(F)CNc2ccc3CCC(=O)c3c2)CC1
Structure:
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